The Protein Folding Database
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  Statistics
Version: 2.2
Last Update: 8-Jun-2007
Entries: 296
Proteins: 69
Families: 52
Species: 29
ϕ values: 230 (5 proteins)
Locations of visitors to this page
  Latest Additions
ACBP (3 WT)
FRB (6 WT)
CI2 (3 WT, 202 mutants)
HPr (1 WT, 4 mutants)
Im7 (1 WT)
En-HD (1 WT)
Im9 (2 WT)
Abp1 SH3 (1 WT)
CheW (1 WT)
U1A (1 WT)
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Protein Folding Database

Welcome to the Protein Folding Database (PFD), a searchable repository of freely available experimental protein folding data.

You can:

The PFD Team

Acyl Coenzyme A Binding Protein Hypothetical protein YjbJ from Escherichia coli E colicin binding Immunity Protein 7 (ImmE7*) E colicin binding Immunity Protein 9 (ImmE9) Lambda C1 repressor, DNA-binding domain E colicin binding Immunity Protein 9 (ImmE9) Acyl Coenzyme A Binding Protein Acyl Coenzyme A Binding Protein Internalin B, C-terminal domain Apo-azurin Chemotaxis protein CheW Fyn proto-oncogene tyrosine kinase, SH3 domain Alpha-Spectrin SH3 Domain c-src tyrosine kinase SH3 Domain Actin binding protein 1 SH3 domain Activation Domain Of Human Procarboxypeptidase A2 Chymotrypsin Inhibitor 2 Ribosomal protein L9 C-domain FK-506 binding protein Ribosomal protein L23 Acylphosphatase Ribosomal protein L9 N-domain Immunoglobulin-binding protein G Immunoglobulin light chain-binding domain of protein L c-Raf1 RBD Ribosomal protein S6 c-src tyrosine kinase SH2 domain Spliceosomal U1A protein Ubiquitin FK-506 binding protein Chymotrypsin Inhibitor 2 Chymotrypsin Inhibitor 2
generated contact order graph

Moving your mouse over a data point will display that protein's name.
Clicking on a data point will display folding data on that protein.
To view more data on a SCOP Class click on it's name in the legend.


Latest News
  Version 2.2 Update
User:  Mr. Mark Bate   Date:  08/06/2007 11:38am
BLAST
- Blast your sequence against PFD database, PFD entries against PFD or against NCBI Non Redundant DB.

Compare View
- Compare and highlight the similarities and differences between your search results.
Eg. FRB

Export Select Search Results Data
- Simply select which data you want to include & click "export selected data to CSV". (also works with compare view)

Save time, base depositions on Search Results!
- Select the data you want & click the button. (you need to be logged in for this to work)

"+mutants" Search Keyword
- You can now use the search box (in the sidebar) to quickly find a protein & its mutants. Simply add "+mutants" (without the quotes) after the protein name.
Eg. CI2+mutants

Mutant Data Template Upgrade
- You can now upload up to 150 mutants in one deposition using the new mutant templates.

Depositions for busy people
- Don't have time to use our new "base deposition on search result" feature, just paste your data in the textbox & we'll do the deposition for you.

Wiki for the community
- We've opened up our wiki, create an account and share your knowledge.

Kate Fulton, Mark Bate, Ashley Buckle.
  Fixes & Features
User:  Mr. Mark Bate   Date:  30/01/2007 2:15pm
Improved Advanced Search
- Limit searches on any combination of database fields

Search "Field Select"
- Add & remove data columns in your search results

Data Export
- Export the results of any search (including Advanced Search & Field Select) to Comma Seperated Values (CSV) format.

Be sure to check the wiki for a full list of resolved issues & implemented features.

Kate Fulton, Mark Bate, Ashley Buckle
  Version 2.0 released
User:  Dr. Kate Fulton   Date:  06/11/2006 12:14pm
This is the release of version 2.0 of the Protein Folding Database.
We have reworked the entire site with the aim of creating the definative resource for protein folding.

So far we have populated the database with data from the paper "Maxwell et al (2005) Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins". Protein Sci. (view PubMed), with the addition of a set of mutants to test the phi-value import.
Now that the database and website does most of the basic things we want we are expanding the dataset.

Much of the development time was spent on deposition tools, so we encourage you to use these to deposit your own data - we think that a comprehensive collection of folding data will benefit everyone in the field.

Note that the site is still undergoing constant development, and there are bugs, but we are gradually fixing these.
We would appreciate feedback, comments, criticisms, but most of all data deposition. If you think we can improve the deposition tools, please let us know.

We are particularly interested in representing data graphically, and have started this with the contact order plot as well as plotting raw data such as chevron and equilibrium curves.

Kate Fulton, Mark Bate, and Ashley Buckle